GO

DILIscore = 0.608 *loge(daily dose/mg) +0.227*logP+2.833*(RM formation= 1 if Yes or 0 if No)  

DILIscore: > 6, high risk; 3-6, moderate risk; < 3, low risk  

Reference:

1. Chen, M., Borlak, J. and Tong, W. A Model to predict severity of drug‐induced liver injury in humans. Hepatology, 2016, 64(3): 931-940.   Abstract





NCTR Bioinformatics Tools      NCTR      FDA